What are the Physical and Chemical Properties of HPMC?

As Hydroxypropyl Methylcellulose Suppliers, I would like to share with you.

Hypromellose is a kind of non-ionic cellulose mixed ether. It is a semi-synthetic, inactive, viscoelastic polymer, often used as a lubricant in ophthalmology, or as an excipient or excipient in oral medicine.

Physical properties

Appearance and properties: white or almost white fibrous or granular powder

Density: 1.39 g/cm3

Solubility: almost insoluble in absolute ethanol, ether, acetone; swelling in cold water into a clear or slightly turbid colloidal solution

Stability: The solid is flammable and incompatible with strong oxidants.

Chemical nature

1. Appearance: white or almost white powder.

2. Granularity; the pass rate of 100 mesh is greater than 98.5%; the pass rate of 80 mesh is 100%. Special specifications have a particle size of 40-60 mesh.

3. Carbonization temperature: 280-300℃

4. Apparent density: 0.25-0.70g/cm (usually around 0.5g/cm), specific gravity 1.26-1.31.

5. Discoloration temperature: 190-200℃

6. Surface tension: 42-56dyn/cm for 2% aqueous solution.

7. Solubility: soluble in water and some solvents, such as ethanol/water, propanol/water in appropriate proportions. The aqueous solution has surface activity. High transparency and stable performance. Different specifications of products have different gel temperatures, and solubility changes with viscosity. The lower the viscosity, the greater the solubility. Different specifications of HPMC have different performances. The dissolution of HPMC in water is not affected by pH.

8. As the content of methoxy group decreases, the gel point of HPMC increases, the water solubility decreases, and the surface activity also decreases.

9. HPMC also has thickening ability, salt resistance, low ash powder, pH stability, water retention, dimensional stability, excellent film-forming properties, and wide range of enzyme resistance, dispersibility and adhesion.

Our company also has HPMC for Wall Putty on sale, welcome to contact us.



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